Category: Muscular Dystrophy

Rationale A muscular dystrophy is a group of diseases that cause progressive weakness and loss of muscle mass. It is a genetic X-linked recessive inherited disorder which primally effects males. It is passed down through the mother who is a carrier of the gene. Becker Muscular Dystrophy (BMD) is one of the nine different types…

Introduction: An ongoing investigation has indicated that CRISPR can be utilized as a generative method that can treat Duchenne muscular dystrophy. Because of an examination in mice, it could be created as a remedial choice for humans Duchenne muscular dystrophy is caused by a defective gene for dystrophin. Duchenne muscular dystrophy occurs in about 1…

Inquiry Question: Should funding be allocated towards further research into genome editing as a clinical treatment for Duchenne Muscular Dystrophy? Introduction: Duchenne Muscular Dystrophy is a form of inherited neuromuscular disease found in children, causing progressive degeneration of muscle stability. It is as a result of a mutation in the DMD gene coding for the…

Duchenne’s Muscular Dystrophy is a genetic disorder linked to the X chromosome that is caused by a deficiency in the protein dystrophin (Mendell et al., 1995). This disease weakens skeletal and cardiac muscles, and may pose obstacles when sitting, standing, walking, and speaking. Treatment by myoblast transfer showed promising results in animal trials. This method…

Introduction: Muscular dystrophies are defined as a group of heterogeneous group of diseases characterized by muscle weakness (Rahimov et al, 2013). There are different kinds of muscular dystrophy like Duchenne, Becker, Myotonic, Congenital, Emery-Dreifuss, Facioscapulohumeral, Limb-girdle, Distal, and Oculopharyngeal (Table 1). The most common form is Duchenne muscular dystrophy (DMD). 1 in every 3500 to…

Muscular dystrophy is a genetic disease that currently has no cure. There are medical treatments and medications that can help ease symptoms and manage the disease. We will discuss further later what these treatments and medications are and how they can help the patient. Let’s first briefly discuss the history of muscular dystrophy and how…